Acetyl-L-Carnitine (ALC) is a naturally occurring form of L-Carnitine, a vitamin-like nutrient synthesized in the body from the amino acids lysine and methionine. ALC serves as a transport molecule for “active acetate,” which is a source of fuel for metabolic processes that take place in cells. ALC carries active acetate (the “Acetyl” portion) directly into the mitochondrion, the cell’s energy-generating structure. Active acetate is used to produce cellular energy in the form of ATP. Both L-Carnitine and ALC serve as fat carriers. Unlike L-Carnitine, ALC readily crosses the blood-brain barrier, where it has specific benefits for brain neurons. When taken orally, ALC has been shown to increase ALC levels in both blood and cerebrospinal fluid, demonstrating its uptake in the brain.
Best Acetyl-L-Carnitine consists of Biosint™ Acetyl-L-Carnitine, which is manufactured in Italy by the Sigma Tau company. It is derived from a base of pharmaceutical-grade L-Carnitine manufactured using an FDA-approved process that fully complies with international monograph standards for carnitine production. Known as a global leader in L-Carnitine research, Sigma Tau holds numerous patents for production of L-Carnitine, and its L-Carnitine derivatives, such as ALC, which are used in clinical trials.
Supports cognitive function
ALC has been studied for its effect on cognitive performance and emotional health in the elderly.
In a single-blind, placebo-controlled trial, 481 elderly subjects exhibiting mild memory impairment improved their scores on a memory test after taking 1500 mg of ALC a day for 90 days.2 Hospitalized elderly people taking ALC have shown improvements in mental outlook.
Supports biosynthesis of acetylcholine, a key neurotransmitter for brain and nerve function
Brain function requires coordinated communication between brain cells. Brain and nerve cells (“neurons”) communicate across tiny cell-to-cell gaps called “synapses.
” The passage of an electrical impulse from one neuron to the next requires a “neurotransmitter.
” When an electrical signal arrives at the synaptic junction, the neuron releases a neurotransmitter into the synapse.
The neuron on the other side of the synapse contains receptors for the neurotransmitter; these receptors bind the neurotransmitter, triggering a series of chemical events that sends a new electrical signal down the membrane of the receiving neuron. Neurotransmitters work together like an orchestra to transmit information throughout the brain and nervous system.
Acai is an exotic palm fruit from the Amazonian rain forest, the story of acai dates back hundreds of years to its use by the peoples of the Orinoco basin area of Brazil.
The fruit was treasured as a source of sustenance for the people.
Scientific research has confirmed the high nutritional value of acai fruit and uncovered its potent antioxidant benefits. Analyses have shown that acai is one of the richest sources of anthocyanins in the world, substances known to be powerful free radical scavengers
Best Acai features OptiAcai™, a potent, freeze-dried form of acai fruit. Ripe acai fruits that grow wild in the Amazon are harvested at their peak the skin and pulp are separated from their seeds and dried in a unique freeze-drying process that preserves the wholesome goodness of the entire fruit, including the important anthocyanins. This ensures that OptiAcai™ retains powerful, beneficial antioxidant properties, which serve to promote cellular health.
Beneficial Antioxidant Protection
Our body produces free radicals as a byproduct of many metabolic processes.
Free radicals are molecules with unpaired electrons that have the potential of causing harm if not adequately neutralized by the body’s antioxidant system. While some free radical production is necessary for metabolism and detoxification, excessive amounts of free radicals may lead to compromised health.
Maintains Cellular Health
Acai’s deep purple coloration makes it a rich source of beneficial polyphenols.
While these compounds are potent antioxidants as outlined above, they also confer benefits beyond their free radical scavenging activity.
A number of these phytochemicals are known to have beneficial effects on cellular health.
Some mechanisms employed by polyphenols include the induction or inhibition of enzyme function and alteration of signal transduction, enhancing the ability of cells to communicate more effectively with each other. Many polyphenols are considered “biological response modifiers”, since they possess multiple effects, including the ability to decrease oxidative stress to cells. Since polyphenols are water soluble, they are also well-absorbed and assimilated, allowing them to efficiently promote cellular health.